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KMID : 1156220160420030141
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Journal of Environmental Health Sciences
2016 Volume.42 No. 3 p.141 ~ p.146
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Estimation of Humidifier Disinfectant Amounts Inhaled into the Respiratory System
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Park Dong-Uk
Ryu Seung-Hun
Lim Heung-Kyu
Kim Sun-Kyung
Roh Hyun-Seog
Cha Won-Seok
Park Doo-Yong
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Abstract
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In South Korea, many cases of humidifier disinfectant-associated lung injury (HDLI) have been reported among people who used humidifier products containing humidifier disinfectant (HD). The objectives of this study are to estimate both airborne HD concentration in the room where HD was used and the amount of humidifier disinfectant absorbed into the respiratory system. Information and data on the HDs were collected using a structured questionnaire and home environmental investigations include the volume of HD (ml) and hours used per day, concentration of disinfectants contained in the HD brand (μg/ml), volume of the room (m3), assumed ventilation rate (m3/hr) and breathing rate assumed (m3/hr). We used children aged under five years old as a sample and estimated both airborne HD concentrations and amount of HD absorbed into the respiratory system. The estimated airborne concentration of HD in the room ranged from 68 to 369 μg/m3 for PHMG (polyhexamethylene guanidine phosphate) and from 16 to 239 μg/m3 for PGH (oligo (2-(2-ethoxy) ethoxyethyl guanidine). The amount of HD absorbed in the respiratory system per day was estimated to range from 227 to 1,225 μg for PHMG and from 53 to 794 μg for PGH. In conclusion, a great amount of HD was likely absorbed into respiratory system, likely beyond the level of the capacity of the immune system to remove the HD
absorbed.
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KEYWORD
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Estimation of Humidifier Disinfectant Amounts Inhaled into the Respiratory System
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